This new book, from the editor of the highly successful Pharmaceutical Analysis, sets out to define the area of pharmaceutical chemistry as distinct from medicinal chemistry. It focuses less on prototypes of drugs that perhaps never came to market an ...view more
This new book, from the editor of the highly successful Pharmaceutical Analysis, sets out to define the area of pharmaceutical chemistry as distinct from medicinal chemistry. It focuses less on prototypes of drugs that perhaps never came to market and more on the drugs currently in use. The emphasis in the book is on the physicochemical properties of drug molecules and, in so far as they are known, the way that these properties govern the interaction of the drug with its target. Important physicochemical properties include pKa and partition coefficient and the properties of the structural elements within the drug which provide interactions with the target via a range of intermolecular forces. The last fifteen years has seen a great advance in the knowledge of protein structures and a strong emphasis is given to the interaction of drugs with proteins which shape the majority of drug mechanisms.
This new book, from the editor of the highly successful Pharmaceutical Analysis, sets out to define the area of pharmaceutical chemistry as distinct from medicinal chemistry. It focuses less on prototypes of drugs that perhaps never came to market and more on the drugs currently in use. The emphasis in the book is on the physicochemical properties of drug molecules and, in so far as they are known, the way that these properties govern the interaction of the drug with its target. Important physicochemical properties include pKa and partition coefficient and the properties of the structural elements within the drug which provide interactions with the target via a range of intermolecular forces. The last fifteen years has seen a great advance in the knowledge of protein structures and a strong emphasis is given to the interaction of drugs with proteins which shape the majority of drug mechanisms.
Key Features
Focus on intramolecular actions
Mechanisms of action richly illustrated
Self-assessment included
Comprehensive chapters on vitamins and biotechnological products
Author Information
By David G. Watson, BSc, PhD, PGCE, Senior Lecturer in Pharmaceutical Sciences, Strathclyde Institute of Pharmaceutical and Biomedical Sciences, University of Strathclyde, Glasgow, UK
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https://www.mea.elsevierhealth.com/pharmaceutical-chemistry-9780443072321.html95826Pharmaceutical Chemistryhttps://www.mea.elsevierhealth.com/media/catalog/product/9/7/9780443072321_1.jpg51.7168.95USDInStock/Medicine and Surgery/Pharmacy/Medicine and Surgery/Pharmacology/Medical Students/Pharmacology/Books/Students/Pharmacology10478997711584525503914718137337410541514512010537This new book, from the editor of the highly successful <i>Pharmaceutical Analysis</i>, sets out to define the area of pharmaceutical chemistry as distinct from medicinal chemistry. It focuses less on prototypes of drugs that perhaps never came to market and more on the drugs currently in use. The emphasis in the book is on the physicochemical properties of drug molecules and, in so far as they are known, the way that these properties govern the interaction of the drug with its target. Important physicochemical properties include pKa and partition coefficient and the properties of the structural elements within the drug which provide interactions with the target via a range of intermolecular forces. The last fifteen years has seen a great advance in the knowledge of protein structures and a strong emphasis is given to the interaction of drugs with proteins which shape the majority of drug mechanisms. This new book, from the editor of the highly successful <i>Pharmaceutical Analysis</i>, sets out to define the area of pharmaceutical chemistry as distinct from medicinal chemistry. It focuses less on prototypes of drugs that perhaps never came to market and more on the drugs currently in use. The emphasis in the book is on the physicochemical properties of drug molecules and, in so far as they are known, the way that these properties govern the interaction of the drug with its target. Important physicochemical properties include pKa and partition coefficient and the properties of the structural elements within the drug which provide interactions with the target via a range of intermolecular forces. The last fifteen years has seen a great advance in the knowledge of protein structures and a strong emphasis is given to the interaction of drugs with proteins which shape the majority of drug mechanisms.USD00add-to-cart97804430723212011 and earlierProfessionalBy David G. Watson, BSc, PhD, PGCE20111Book189w x 246h (7.44" x 9.68")Approx. 843 illustrations (13 in full color)Churchill Livingstone6529 Feb 2011PRINT ON DEMAND - DELIVERY CAN TAKE UP TO 10 DAYSBy <STRONG>David G. Watson</STRONG>, BSc, PhD, PGCE, Senior Lecturer in Pharmaceutical Sciences, Strathclyde Institute of Pharmaceutical and Biomedical Sciences, University of Strathclyde, Glasgow, UKBooksNoNoNoNoPlease SelectPlease SelectPlease Select
